Welcome to Module 3

Module Learning Outcomes

Upon successful completion of this module, you will be able to:

Chapter 7

Chapter 8...

Define the term enzyme, including physical composition and structure.
Classify enzymes according to the International Union of Biochemistry.
List the different factors affecting the rate of an enzymatic reaction.
Diagram enzyme kinetics, including zero-order and first-order kinetics.
Explain why the measurement of plasma enzyme concentrations is clinically useful.
Differentiate which enzymes are useful in the diagnosis of various disorders, including cardiac, hepatic, bone, and muscle malignancies, and acute pancreatitis
Discuss the tissue sources, diagnostic significance, clinical assays, and the sources of error for the following enzymes: creatine kinase, lactate dehydrogenase, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, acid phosphatase, γ-glutamyltransferase, 5'-nucleotidase, amylase, lipase, and glucose-6-phosphate dehydrogenase.
Evaluate patient plasma enzyme concentrations in relation to disease states.
State the clinical importance for detecting macroenzymes.
Specify the role of enzymes in drug metabolism.

(CLO = Course Learning Outcome)

To Do

Please read/watch all of the module learning materials (readings, presentations, videos, etc.) and complete all assignments/assessments listed below. If you have questions, please contact the course instructor or ask in the Questions About This Course forum.

Readings and Presentations:

Please read:
- Chapter 7-Non Protein Nitrogen Compounds and
- Chapter 8 -Enzymes
- Ch 4 pages 102-112 only (Electrochemistry and Osmometry)
Presentations: Please review PPT and use to take notes from textbook readings

Videos:

Narrated videos:
- Ch 7 not narrated--since we are doing zoom and cannot effectively break into groups, we will do this in class. I will record it so you can also review at a later date if needed.
- Ch 8: https://youtu.be/nhfh5F5fVOU

Assignments/Assessments:

Complete the following assignments by the date and time indicated on each assignment page.

Pre-lab #3 Glucometer. Be sure that you READ the lab, not just the pre-lab.
Module 3 Homework
Rminders:
- Complete and upload labs 1 and 2 by 9.17.24
- Complete lab math assignment handed out in class by 9.19.24
- Quiz 1 Chapters 1,3,6

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